A human model of immune-driven liver injury Some drugs that pass early safety testing can still cause idiosyncratic drug-induced liver injury (iDILI)—a rare immune reaction that can lead to severe ...

Surgeons have now published the first report of a gene-edited pig liver transplanted into a person. The liver, which came from a genetically modified pig, appeared to stay active, producing bile and ...

Researchers successfully implanted a genetically modified pig liver into a human, proving that such an organ can function for an extended period. The graft supported essential liver processes before ...

Doctors in China have become the first to report details about a transplant of a genetically modified pig liver into a human. The liver was transplanted last year into a person who was brain-dead, and ...

In the past year, doctors have performed history-making transplants, placing genetically modified pig kidneys and pig hearts into patients. Now, a group of doctors and scientists in China report they ...

The transplanted portion of the genetically modified pig liver was removed after 38 days, and the patient, who had advanced liver cancer and cirrhosis, died several months later. By Roni Caryn Rabin ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

Doctors have now used a gene-edited pig liver to keep a human alive, not as a thought experiment in a lab but as a real bridge for a failing organ. The procedure signals a turning point in transplant ...