The endoderm is the innermost layer of cells in very early vertebrate and insect embryos. It is one of the three primary germ cell layers and gives rise to epithelial tissue lining some organs, ...
An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. It ...
An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen. The ...
Foxa transcription factors help endow the competence to activate liver genes in development by binding to regulatory sequences in precursor endoderm and opening a local domain of chromatin. Fibroblast ...
Pluripotent stem cells, created from human skin or mouse ear tissue, are shown here becoming endoderm cells. The endoderm is one of the three primary germ layers that ultimately contribute to the ...
How did the gut, the skin and musculature evolve? This question concerns scientists for more than a century. Through the investigation of the embryonic development of sea anemones, a very old animal ...
Diabetes. 2013;62(10):3514-3522. In summary, our data do not support an early phase of endocrine differentiation in human embryos analogous to primary transition during mouse development, and we did ...
Interim results from a multicenter clinical trial demonstrate insulin secretion from engrafted cells in patients with type 1 diabetes. The safety, tolerability, and efficacy of the implants, which ...
Metastasis remains the primary challenge to reducing cancer deaths worldwide, says Memorial Sloan Kettering Cancer Center (MSK) gastrointestinal oncologist Karuna Ganesh, MD, Ph.D.. That's when a ...
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